Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.64 |
| ▸ | HTR2A | P28223 | 7/20 | 0.64 |
| ▸ | HTR1A | P08908 | 5/20 | 0.64 |
| ▸ | DRD3 | P35462 | 5/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114667 | 0.92 | HRH3 (0.59) | DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL2004136 | 0.87 | DRD2 (0.65) | DRD2HTR2AHTR1A | |
| SCHEMBL12403746 | 0.86 | DRD2 (0.66) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL4244520 | 0.83 | DRD2 (0.67) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL1114311 | 0.82 | DRD2 (0.62) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL12403673 | 0.82 | LMNA (0.72) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL29771174 | 0.82 | DRD2 (0.64) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL1114755 | 0.81 | DRD2 (0.59) | DRD2HTR2AHTR1ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL1114457 | 0.81 | LMNA (0.74) | DRD2HTR2AHTR1ADRD3DRD4 | |
| SCHEMBL2002856 | 0.80 | DRD2 (0.55) | DRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279179-B1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2014-09-17 | — | — | EP | claimed |
| US-8772299-B2 | Phenyl piperazine compounds, pharmaceutical composition including the same and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-07-08 | — | — | US | claimed |
| EP-2279179-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2011-02-02 | — | — | EP | claimed |
| US-20090298831-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-12-03 | — | — | US | claimed |
| WO-2009145591-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | claimed |
| EP-2279179-B1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2014-09-17 | — | — | EP | disclosed |
| EP-2279179-B1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2014-09-17 | — | — | EP | disclosed |
| US-8772299-B2 | Phenyl piperazine compounds, pharmaceutical composition including the same and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-07-08 | — | — | US | disclosed |
| US-8772299-B2 | Phenyl piperazine compounds, pharmaceutical composition including the same and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-07-08 | — | — | US | disclosed |
| US-8772299-B2 | Phenyl piperazine compounds, pharmaceutical composition including the same and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-07-08 | — | — | US | disclosed |
| CN-102046610-B | Phenyl piperazine compounds, pharmaceutical composition including the same, and use thereof | SK HOLDINGS CO LTD | 2013-06-05 | — | — | CN | disclosed |
| US-7985752-B2 | Phenyl piperazine compounds, pharmaceutical composition including the same and use thereof | SK HOLDINGS CO., LTD. (KR) | 2011-07-26 | — | — | US | disclosed |
| US-20110118264-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2011-05-19 | — | — | US | disclosed |
| US-20110118264-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2011-05-19 | — | — | US | disclosed |
| EP-2279179-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2011-02-02 | — | — | EP | disclosed |
| US-20090298831-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-12-03 | — | — | US | disclosed |
| US-20090298831-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-12-03 | — | — | US | disclosed |
| US-20090298831-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2009-12-03 | — | — | US | disclosed |
| WO-2009145591-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009145591-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298831-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | HTR5A, HTR1A, HTR2A | DRD2 62/4885HTR2A 3/4885HTR1A 2/4885 |
| US-20110118264-A1 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME AND USE THEREOF | HTR5A, HTR1A, HTR2A | DRD2 60/4885HTR2A 3/4885HTR1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.