Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110239 | 0.93 | NSD2 (0.64) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL1320296 | 0.87 | HDAC2 (0.50) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL6253635 | 0.86 | HDAC2 (0.72) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL12119308 | 0.84 | HDAC2 (0.47) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL1110388 | 0.82 | HDAC2 (0.43) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL1110390 | 0.81 | HDAC2 (0.45) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL1110584 | 0.79 | PLK1 (0.65) | HDAC8KDM4EALDH1A1 | |
| SCHEMBL27903143 | 0.78 | HDAC2 (0.73) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL1110394 | 0.77 | HDAC2 (0.41) | NSD2HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL4245444 | 0.75 | TUBB (0.49) | HDAC2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127723-A1 | NEW ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |