Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.42 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.42 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537790 | 0.90 | NQO2 (0.43) | ABCB1KCNN2KCNN3KCNN1NQO2 | |
| SCHEMBL3143094 | 0.90 | NQO2 (0.43) | ABCB1KCNN2KCNN3KCNN1NQO2 | |
| SCHEMBL3162728 | 0.90 | NQO2 (0.43) | ABCB1KCNN2KCNN3KCNN1NQO2 | |
| Hydrochloric Acid SCHEMBL9427134 | 0.89 | KCNN2 (0.42) | ABCB1KCNN2KCNN3KCNN1NQO2 | |
| SCHEMBL7911834 | 0.83 | CYP3A4 (0.43) | NQO2MTNR1AMTNR1BCHRM2HTR1A | |
| SCHEMBL31549 | 0.83 | CYP3A4 (0.43) | NQO2MTNR1AMTNR1BCHRM2HTR1A | |
| SCHEMBL383341 | 0.83 | CYP3A4 (0.43) | NQO2MTNR1AMTNR1BCHRM2HTR1A | |
| SCHEMBL7436614 | 0.83 | CYP3A4 (0.43) | NQO2MTNR1AMTNR1BCHRM2HTR1A | |
| SCHEMBL31936524 | 0.83 | CYP3A4 (0.43) | NQO2MTNR1AMTNR1BCHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL9427970 | 0.81 | MAOA (0.42) | KCNN2KCNN3KCNN1NQO2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076325-B2 | 1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-12-13 | — | — | US | disclosed |
| US-20090069296-A1 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069296-A1 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | OXER1, NR1H3, OXSR1 | ABCB1 355/4885KCNN2 827/4885KCNN3 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.