Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248473 | 0.91 | FAAH (0.52) | GRIN1GRIN2BGAAPOLBMAPT | |
| SCHEMBL4244729 | 0.91 | GAA (0.56) | GAAPOLBMAPTNPSR1 | |
| SCHEMBL4245365 | 0.86 | POLB (0.54) | GRIN1GRIN2BGAAPOLBMAPT | |
| SCHEMBL4243148 | 0.83 | GAA (0.55) | GRIN1GRIN2BGAAPOLBMAPT | |
| SCHEMBL4591294 | 0.81 | GRIN1 (0.51) | GRIN1GRIN2BPOLBMAPTCCR3 | |
| SCHEMBL4768629 | 0.81 | GAA (0.67) | GAAPOLBMAPTNPSR1 | |
| SCHEMBL28942715 | 0.81 | PARP14 (0.51) | GRIN2BGAAPOLBMAPTNPSR1 | |
| SCHEMBL4578087 | 0.81 | GRIN1 (0.62) | GRIN1GRIN2BCCR3 | |
| SCHEMBL9444298 | 0.79 | POLB (0.51) | POLBMAPTNPSR1 | |
| SCHEMBL2925616 | 0.79 | MEN1 (0.60) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-07-02 | — | — | US | disclosed |
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170901-A1 | Benzoyl Urea Derivatives | OPRM1, GRIN2C, GRIN3A | GRIN1 5/4885GRIN2B 7/4885GAA 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.