Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23520537 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL6654904 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EMAPTPOLBLMNA | |
| SCHEMBL23520541 | 0.79 | PLK1 (0.48) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL23520545 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL23520538 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL7478784 | 0.77 | MAPT (0.62) | ALDH1A1KDM4EMAPTPOLBCA9 | |
| SCHEMBL26111441 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL4893880 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTPOLBCSNK2A2 | |
| SCHEMBL4591133 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL22114489 | 0.74 | MAP2K1 (0.43) | ALDH1A1KDM4EMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050457-A1 | Radiopaque cyanoacrylate compositions | BioNexus, Inc. (US) | 1982-04-28 | — | — | EP | claimed |
| US-20210177851-A1 | NOVEL BENZYLAMINO SUBSTITUTED QUINAZOLINES AND DERIVATIVES AS SOS1 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-06-17 | — | — | US | disclosed |
| EP-2880033-B1 | CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2020-06-17 | — | — | EP | disclosed |
| US-20090192592-A1 | POROUS IMPLANT STRUCTURE | CINVENTION AG (DE) | 2009-07-30 | — | — | US | disclosed |
| US-20080249638-A1 | BIODEGRADABLE THERAPEUTIC IMPLANT FOR BONE OR CARTILAGE REPAIR | CINVENTION AG (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080249637-A1 | PARTIALLY BIODEGRADABLE THERAPEUTIC IMPLANT FOR BONE AND CARTILAGE REPAIR | CINVENTION AG (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080248086-A1 | CURABLE THERAPEUTIC IMPLANT COMPOSITION | CINVENTION AG (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080200976-A1 | CARBON STENTS | CINVENTION AG (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080195198-A1 | DEGRADABLE POROUS IMPLANT STRUCTURE | CINVENTION AG (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080195196-A1 | RESERVOIR IMPLANTS AND STENTS | CINVENTION AG (DE) | 2008-08-14 | — | — | US | disclosed |
| EP-0619716-B1 | CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1998-08-05 | — | — | EP | disclosed |
| US-5733525-A | Method of EII using a water insoluble particulate agent | NYCOMED IMAGING AS (NO) | 1998-03-31 | — | — | US | disclosed |
| US-5651955-A | Method of electrical impedance imaging using ionic metal chelates | NYCOMED IMAGING AS (NO) | 1997-07-29 | — | — | US | disclosed |
| US-5639444-A | Method of electrical impedance imaging using a triiodophenyl compound or gas encapsulated microbubbles | NYCOMED IMAGING AS (NO) | 1997-06-17 | — | — | US | disclosed |
| US-5346690-A | Composition of a superparamagnetic or ferromagnetic particle and an X-ray contrast agent for MRI | NYCOMED IMAGING AS (NO) | 1994-09-13 | — | — | US | disclosed |
| EP-0414288-B1 | Contrast media | NYCOMED IMAGING AS (NO) | 1994-03-23 | — | — | EP | disclosed |
| EP-0414287-B1 | Particulate contrast media | NYCOMED IMAGING AS (NO) | 1994-01-19 | — | — | EP | disclosed |
| US-5242683-A | Gastrointestinal tract, side effect reduction | NYCOMED IMAGING AS (NO) | 1993-09-07 | — | — | US | disclosed |
| EP-0414287-A1 | Particulate contrast media | NYCOMED IMAGING AS (NO) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414288-A1 | Contrast media | NYCOMED IMAGING AS (NO) | 1991-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177851-A1 | NOVEL BENZYLAMINO SUBSTITUTED QUINAZOLINES AND DERIVATIVES AS SOS1 INHIBITORS | SOS1, SOS2, SOST | ALDH1A1 2728/4885KDM4E 3689/4885MAPT 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.