SCHEMBL4244965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5617788	0.91	TLR7 (0.44)	TLR7TLR8NLRP3
	SCHEMBL14572628	0.89	TLR7 (0.43)	TLR7TLR8NLRP3
	SCHEMBL4252232	0.89	SMN1; SMN2 (0.41)	TLR7TLR8KDM4EALDH1A1GLA
	SCHEMBL14572637	0.87	TLR8 (0.49)	TLR7TLR8NLRP3NUDT1
	SCHEMBL4243090	0.87	TLR7 (0.51)	TLR7TLR8NLRP3
	Hydrochloric Acid SCHEMBL4237235	0.86	TLR8 (0.48)	TLR7TLR8NLRP3NUDT1
	SCHEMBL4236723	0.83	NLRP3 (0.41)	TLR7TLR8NLRP3NUDT1
	SCHEMBL4236745	0.83	TLR7 (0.46)	TLR7TLR8NLRP3
	SCHEMBL4236719	0.83	NLRP3 (0.41)	TLR7TLR8NLRP3NUDT1
	SCHEMBL31337596	0.81	TLR7 (0.59)	TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.