Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27153658 | 1.00 | USP2 (0.45) | USP2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL14864848 | 0.72 | MAPK8 (0.38) | USP2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL545028 | 0.69 | KDM4E (0.50) | USP2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL14373986 | 0.68 | USP2 (0.64) | USP2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL14373987 | 0.67 | KDM4E (0.47) | USP2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL18358350 | 0.64 | CHEK1 (0.39) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL11029949 | 0.64 | SMN1; SMN2 (0.33) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL18788152 | 0.63 | USP2 (0.57) | USP2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL9036763 | 0.62 | ADORA3 (0.67) | HSD17B10CYP1A2PARP1SMN1; SMN2TP53 | |
| SCHEMBL461719 | 0.61 | NPC1 (0.59) | USP2TSHRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894897-A | Heteroaromatic compounds for the treatment of neurological disorders | 苏文生命科学有限公司 | 2025-04-25 | — | — | CN | disclosed |
| EP-2035426-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007144384-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2007-12-21 | — | — | WO | disclosed |