Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | LPO | P22079 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493198 | 0.82 | TBXAS1 (0.32) | MAPK8DYRK1ACLK4DYRK1BMEN1 | |
| SCHEMBL11025542 | 0.80 | KDM4E (0.33) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL10843815 | 0.64 | HSD17B10 (0.38) | MEN1LMNAPABPC1KMT2AHPGD | |
| SCHEMBL4244986 | 0.64 | USP2 (0.45) | SMN1; SMN2CA1LMNAKDM4EALDH1A1 | |
| SCHEMBL27153658 | 0.64 | USP2 (0.45) | SMN1; SMN2CA1LMNAKDM4EALDH1A1 | |
| SCHEMBL11026113 | 0.62 | KDM4E (0.31) | KDM4EALDH1A1HPGD | |
| SCHEMBL14341766 | 0.60 | TBXAS1 (0.31) | TBXAS1 | |
| SCHEMBL10844582 | 0.60 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL31136330 | 0.60 | TNKS (0.33) | KDM4EALDH1A1 | |
| SCHEMBL26734621 | 0.59 | SMN1; SMN2 (0.37) | SMN1; SMN2CA1CLK4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473570-A | BRONCHODILATOR AGENTS | RIKER LABORATORIES, INC. (US) | 1984-09-25 | — | — | US | disclosed |