SCHEMBL4245134

SCHEMBL4245134

OB(O)Oc1cc(C(F)(F)F)cc(C(OCC(F)(F)F)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.31
RPS6KA3 P51812 1/20 0.31
JAK3 P52333 1/20 0.31
SOD1 P00441 1/20 0.31
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31611836 1.00 IDO1 (0.31) IDO1RPS6KA3JAK3SOD1CES2
SCHEMBL4245131 0.88 IDO1 (0.33) IDO1SOD1
SCHEMBL466921 0.82 CES2 (0.41) IDO1RPS6KA3JAK3SOD1CES2
Boric Acid SCHEMBL27540523 0.81 IDO1 (0.33) IDO1CES2
SCHEMBL27554599 0.81 MGLL (0.42) IDO1CES2
SCHEMBL5808191 0.81 NOTUM (0.33) CES2
Boric Acid SCHEMBL27554658 0.80 IDO1 (0.32) IDO1CES2
Boric Acid SCHEMBL27576908 0.80 IDO1 (0.32) IDO1CES2
Boric Acid SCHEMBL28747018 0.80 IDO1 (0.32) IDO1CES2
SCHEMBL23633171 0.80 CES2 (0.40) IDO1RPS6KA3JAK3SOD1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901711-A UV-active derivatives of Pd (AcAc) 2-catalyzed polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-08-12 CN claimed
CN-114901712-A AsPd (AcAc) of optical Material 2 UV active derivatives of L catalyzed polycycloolefin compositions 普罗米鲁斯有限责任公司 2022-08-12 CN claimed
CN-101031595-A One-component cationic palladium pre-initiator for the latent polymerization of cycloolefins PROMERUS LLC (US) 2007-09-05 CN claimed
CN-1554680-A In mold addition polymerization composition of norbornene-type monomers and its crosslinking addition polymer ס�ѵ�ľ��ʽ���� 2004-12-15 CN claimed
US-20030023013-A1 Catalyst and methods for polymerizing cycloolefins THE B.F.GOODRICH COMPANY 2003-01-30 US claimed
US-20020052454-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS SUMITOMO BAKELITE CO., LTD. (JP) 2002-05-02 US claimed
CN-1333788-A In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes GOODRICH CO B F (US) 2002-01-30 CN claimed
CN-1290275-A Catalyst and process for polymerization of cycloolefin GOODRICH CO B F (US) 2001-04-04 CN claimed
US-20240002586-A1 CURABLE COMPOSITIONS, COMPOSITE FOAM, METHOD OF MAKING THE SAME, AND ARTICLE INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2024-01-04 US disclosed
CN-114901711-A UV-active derivatives of Pd (AcAc) 2-catalyzed polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-08-12 CN disclosed
CN-114901712-A AsPd (AcAc) of optical Material 2 UV active derivatives of L catalyzed polycycloolefin compositions 普罗米鲁斯有限责任公司 2022-08-12 CN disclosed
WO-2022118175-A1 CURABLE COMPOSITIONS, COMPOSITE FOAM, METHOD OF MAKING THE SAME, AND ARTICLE INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-09 WO disclosed
US-7902109-B2 Organometallic compound, catalyst for polymerization of polar group-containing norbornene and process for producing norbornene polymer FUJIFILM CORPORATION (JP) 2011-03-08 US disclosed
US-20090247729-A1 ORGANOMETALLIC COMPOUND, CATALYST FOR POLYMERIZATION OF POLAR GROUP-CONTAINING NORBORNENE AND PROCESS FOR PRODUCING NORBORNENE POLYMER FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-6825307-B2 CONTACTING CYCLOOLEFIN MONOMER WITH A HIGH ACTIVITY TRANSITION METAL CATALYST COMPLEX TO OBTAIN POLYCYCLOOLEFIN PROMERUS, LLC 2004-11-30 US disclosed
WO-2004035636-A2 POLYMERIZED CYCLOOLEFINS USING TRANSITION METAL CATALYST AND END PRODUCTS THEREOF PROMERUS, LLC (US) 2004-04-29 WO disclosed
US-20040048994-A1 Polymerized cycloolefins using transition metal catalyst and end products thereof PROMERUS, LLC 2004-03-11 US disclosed
US-20030181607-A1 Polymerized cycloolefins using transition metal catalyst and end products thereof SUMITOMO BAKELITE CO., LTD. (JP) 2003-09-25 US disclosed
US-20030120006-A1 In mold addition polymerization of norbornene-type monomers using group 10 metal complexes THE B.F. GOODRICH COMPANY 2003-06-26 US disclosed
US-20030023013-A1 Catalyst and methods for polymerizing cycloolefins THE B.F.GOODRICH COMPANY 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247729-A1 ORGANOMETALLIC COMPOUND, CATALYST FOR POLYMERIZATION OF POLAR GROUP-CONTAINING NORBORNENE AND PROCESS FOR PRODUCING NORBORNENE POLYMER DDT, PHOSPHO1, POF1B IDO1 3737/4885RPS6KA3 675/4885JAK3 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.