Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436915 | 0.91 | RAB9A (0.36) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL4246225 | 0.87 | ALDH1A1 (0.37) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL3436957 | 0.85 | SMN1; SMN2 (0.35) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| Ethanesulfonic Acid Amide SCHEMBL3436960 | 0.84 | ALDH1A1 (0.37) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL4244574 | 0.84 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL4244576 | 0.83 | RAB9A (0.34) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL6450251 | 0.80 | IRAK4 (0.37) | — | |
| SCHEMBL7057676 | 0.80 | MEN1 (0.32) | RAB9ASMN1; SMN2NR3C1KMT2AMEN1 | |
| SCHEMBL9076246 | 0.79 | SMN1; SMN2 (0.38) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL9076935 | 0.79 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-20090042730-A1 | Substituted Arylketones | HERRMANN STEFAN | 2009-02-12 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-7456133-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-20060252647-A1 | Herbicides; broad active spectrum; on soil and above ground plant parts use | HERRMANN STEFAN | 2006-11-09 | — | — | US | disclosed |
| US-7112554-B2 | Substituted arylketones | BAYER CROPSCIENCE AG (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20040176253-A1 | Substitued arylketones | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
| EP-1387831-A1 | SUBSTITUTED ARYLKETONES | Bayer CropScience AG (DE) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002090336-A1 | SUBSTITUTED ARYLKETONES | BAYER CROPSCIENCE AG (DE) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252647-A1 | Herbicides; broad active spectrum; on soil and above ground plant parts use | CYP1A1, CYP1A2, CYP4X1 | RAB9A 2932/4885SMN1; SMN2 4541/4885TSHR 1785/4885 |
| US-20040176253-A1 | Substitued arylketones | CYP1B1, CYP1A1, CYP2E1 | RAB9A 2755/4885SMN1; SMN2 2728/4885TSHR 1625/4885 |
| US-20090042730-A1 | Substituted Arylketones | CYP1A1, CYP1B1, CYP1A2 | RAB9A 2880/4885SMN1; SMN2 3889/4885TSHR 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.