Propionic Acid

Propionic Acid

SCHEMBL4245247

C1=Cc2c(ccc3ccccc23)OC1.CCC(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.47
MTNR1B P49286 1/20 0.47
CYP1A2 P05177 6/20 0.43
CYP1A1 P04798 5/20 0.43
CYP1B1 Q16678 5/20 0.43
PTGS1 P23219 4/20 0.42
PTGS2 P35354 4/20 0.42
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
CYP2B6 P20813 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL13725740 0.90 MTNR1A (0.46) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
SCHEMBL87841 0.85 CA12 (0.47) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
SCHEMBL1041972 0.85 CA12 (0.47) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
SCHEMBL29756136 0.85 CA12 (0.47) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
Toluene SCHEMBL8134407 0.83 CYP1A2 (0.45) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
Phosphoric Acid SCHEMBL31540356 0.83 CA12 (0.44) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
Phenol SCHEMBL28029036 0.83 CYP1A2 (0.44) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
Biphenyl SCHEMBL27372808 0.83 CYP1A2 (0.52) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
Serine SCHEMBL28952871 0.82 MTNR1A (0.42) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1
SCHEMBL372269 0.78 HPRT1 (0.47) MTNR1AMTNR1BCYP1A2CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009121148-A1 DYE COMPRISING FUNCTIONAL SUBSTITUENT ADVANCED POLYMERIK PTY LTD (AU) 2009-10-08 WO disclosed