SCHEMBL4245330

SCHEMBL4245330

O=Cc1cccc2c(C=O)cccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
LMNA P02545 2/20 0.61
THRB P10828 1/20 0.61
BLM P54132 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
ERN1 O75460 3/20 0.50
TRIM24 O15164 3/20 0.48
TRIM33 Q9UPN9 3/20 0.48
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.48
CYP2A6 P11509 3/20 0.44
IMPDH2 P12268 2/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 2/20 0.44
PABPC1 P11940 1/20 0.44
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29786760 0.88 KMT2A (0.61) MEN1KMT2ALMNATHRBBLM
SCHEMBL982388 0.88 KMT2A (0.61) MEN1KMT2ALMNATHRBBLM
SCHEMBL12807426 0.87 MEN1 (0.48) MEN1KMT2ALMNATHRBBLM
SCHEMBL17422062 0.85 LMNA (0.52) MEN1KMT2ALMNATHRBBLM
SCHEMBL9671258 0.85 ERN1 (0.57) MEN1KMT2ALMNATHRBBLM
SCHEMBL13396441 0.85 KMT2A (0.46) MEN1KMT2ALMNATHRBBLM
SCHEMBL12143561 0.85 ERN1 (0.57) MEN1KMT2ALMNATHRBBLM
SCHEMBL12143563 0.85 ALDH1A1 (0.60) MEN1KMT2ALMNATHRBBLM
SCHEMBL9099854 0.85 ALDH1A1 (0.59) MEN1KMT2ALMNATHRBBLM
SCHEMBL2994301 0.85 ERN1 (0.61) MEN1KMT2ALMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4099744-A None JP disclosed
US-20230330604-A1 MOLECULARLY POROUS CROSS-LINKED MEMBRANES UNIV KING ABDULLAH SCI & TECH (SA) 2023-10-19 US disclosed
WO-2023168192-A1 PROPPANTS DERIVED FROM CROSSLINKING MIXED AROMATIC RESINS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2023-09-07 WO disclosed
US-20230279286-A1 PROPPANTS DERIVED FROM CROSSLINKING MIXED AROMATIC RESINS ExxonMobil Technology and Engineering Company (US) 2023-09-07 US disclosed
US-20230279286-A1 PROPPANTS DERIVED FROM CROSSLINKING MIXED AROMATIC RESINS ExxonMobil Technology and Engineering Company (US) 2023-09-07 US disclosed
US-20230165046-A1 ORGANIC COMPOUND AND SENSOR AND SENSOR EMBEDDED DISPLAY PANEL AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-05-25 US disclosed
US-20230165046-A1 ORGANIC COMPOUND AND SENSOR AND SENSOR EMBEDDED DISPLAY PANEL AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-05-25 US disclosed
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
CN-115551638-A Method and system for physical expansion and imaging of biological samples 耶鲁大学 2022-12-30 CN disclosed
US-11434195-B2 Compositions and methods for treatment of central nervous system tumors UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2022-09-06 US disclosed
EP-0202244-A1 CURED PRODUCTS FROM THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES. DOW CHEMICAL CO (US) 1986-11-26 EP disclosed
WO-1986006386-A1 THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-11-06 WO disclosed
US-4613663-A Thermoplastic and thermosettable products prepared by reacting nitrogen-containing heterocyclic compounds with aromatic aldehydes THE DOW CHEMICAL COMPANY (US) 1986-09-23 US disclosed
WO-1986002932-A1 THERMOSETTABLE POLYMERS OR PREPOLYMERS PREPARED FROM POLYMETHYLATED PYRAZINES AND AROMATIC POLYALDEHYDES AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1986-05-22 WO disclosed
US-4575542-A Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1986-03-11 US disclosed
US-4543388-A Thermosettable polymers or prepolymers prepared from polymethylated pyrazines and aromatic polyaldehydes and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1985-09-24 US disclosed
US-4336373-A HYPOGLYCEMIC AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1982-06-22 US disclosed
US-4172937-A REACTION OF A DIALDEHYDE AND DIAMINE IN A PHENOLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-30 US disclosed
US-4122070-A Fibers and anisotropic melts of polyazomethines E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US disclosed
US-4048148-A Polyazomethine fibers and films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11434195-B2 Compositions and methods for treatment of central nervous system tumors FABP7, FABP1, FABP2 MEN1 2992/4885KMT2A 3428/4885LMNA 3407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.