Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 1.00 |
| ▸ | CTSB | P07858 | 7/20 | 1.00 |
| ▸ | CTSS | P25774 | 7/20 | 1.00 |
| ▸ | CTSV | O60911 | 6/20 | 1.00 |
| ▸ | CTSK | P43235 | 6/20 | 1.00 |
| ▸ | CTSC | P53634 | 6/20 | 1.00 |
| ▸ | CTSF | Q9UBX1 | 5/20 | 1.00 |
| ▸ | CTSH | P09668 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237384 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11245488 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11241271 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11237393 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11245479 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11241262 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11245485 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11250765 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11237386 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK | |
| SCHEMBL11250731 | 0.69 | CTSV (0.52) | CTSLCTSBCTSSCTSVCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078027-A1 | CATHEPSIN PROTEASES INHIBITORS | IRM LLC (BM) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008051763-A1 | CATHEPSIN PROTEASES INHIBITORS | IRM LLC (BM) | 2008-05-02 | — | — | WO | disclosed |