Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50646 | 0.85 | MAPT (0.68) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL94598 | 0.82 | KMT2A (0.59) | MAPTRAB9ALMNAKMT2ASMN1; SMN2 | |
| Benzene SCHEMBL5533098 | 0.79 | MAPT (0.75) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| Acetic Acid SCHEMBL28009208 | 0.79 | MAPT (0.67) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL21679928 | 0.78 | MAPT (0.54) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL934052 | 0.78 | MAPT (0.54) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL2541028 | 0.77 | KMT2A (0.67) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL6272776 | 0.77 | MAPT (0.61) | MAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL23691954 | 0.77 | MAPT (0.59) | MAPTHPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL9615865 | 0.77 | SRD5A2 (0.55) | MAPTHPGDRAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484438-B | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2023-02-03 | — | — | CN | claimed |
| CN-113683474-A | Method for synthesizing norbornane compound | 海南大学 | 2021-11-23 | — | — | CN | claimed |
| CN-111484438-A | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | claimed |
| CN-105906591-A | Synthesis method of 2-amino-gamma-butyrolactone hydrochloride | 中国药科大学 | 2016-08-31 | — | — | CN | claimed |
| EP-1465869-B1 | MODULATORS OF LXR | EXELIXIS PATENT CO LLC (US) | 2013-05-15 | — | — | EP | claimed |
| CN-102653543-A | Preparation method, biological activity and application of 3-substituted type Jolkinolide compound | UNIV CHINA PHARMA | 2012-09-05 | — | — | CN | claimed |
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | claimed |
| EP-1817036-A2 | MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmaceuticals Incorporated (US) | 2007-08-15 | — | — | EP | claimed |
| US-20060270653-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2006-11-30 | — | — | US | claimed |
| WO-2006058303-A2 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-06-01 | — | — | WO | claimed |
| US-4670592-A | BACTERICIDES, FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-02 | — | — | US | claimed |
| US-4574123-A | BACTERICIDES, FUNGICIDES, STERILIZATION, CONTRACEPTIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-03-04 | — | — | US | claimed |
| US-4567174-A | BACTERICIDES, FUNGICIDES, CONTRACEPTIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-28 | — | — | US | claimed |
| EP-0126567-A1 | Bis(1-substituted biguanide) derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-28 | — | — | EP | claimed |
| EP-0125827-A1 | Polyether bisbiguanides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-21 | — | — | EP | claimed |
| EP-0125092-A1 | Bisbiguanide compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0125093-A1 | Diaz(ep)ine bis(N-amidinoamidine) derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0125091-A2 | 4,4'-Alkylenedipiperidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0001841-B1 | TYLOSIN DERIVATIVES | SANRAKU-OCEAN CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |
| US-4029785-A | BACTERICIDES, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1977-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270653-A1 | Modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | MAPT 2337/4885HPGD 1197/4885RAB9A 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.