Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187634 | 0.89 | ALDH1A1 (0.70) | SRD5A2LMNAMAPTHPGDALDH1A1 | |
| SCHEMBL14855596 | 0.87 | ALDH1A1 (0.76) | SRD5A2LMNAHPGDPKMHTT | |
| SCHEMBL9052212 | 0.87 | LTA4H (0.59) | SRD5A2LMNAMAPTHPGDESR1 | |
| SCHEMBL9050342 | 0.87 | SRD5A2 (0.64) | SRD5A2LMNAMAPTHPGDHTT | |
| SCHEMBL8642093 | 0.82 | SRD5A2 (0.68) | SRD5A2HPGDMEN1RAB9AKMT2A | |
| SCHEMBL28841320 | 0.82 | CA2 (0.55) | MAPTALDH1A1RAB9A | |
| SCHEMBL94869 | 0.79 | TSHR (0.71) | SRD5A2ALDH1A1TP53TSHR | |
| SCHEMBL304843 | 0.77 | PARP1 (0.55) | LMNAMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL424551 | 0.77 | MAPT (0.54) | LMNAMAPTHPGDALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28511068 | 0.77 | TSHR (0.67) | SRD5A2ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4099744-A | — | — | None | — | — | JP | disclosed |
| JP-H0499744-A | AROMATIC DIALDEHYDE AND SYNTHESIS THEREOF | AGENCY OF IND SCIENCE & TECHNOL | 1992-03-31 | — | — | JP | disclosed |