Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784071 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL4245806 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL3793417 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL3788934 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL1336271 | 1.00 | POLB (0.49) | POLBFKBP1ANPSR1PREPMITF | |
| SCHEMBL21874256 | 0.87 | NPC1 (0.49) | POLBNPC1RAB9ASMN1; SMN2PDK1 | |
| SCHEMBL1150913 | 0.87 | NPC1 (0.49) | POLBNPC1RAB9ASMN1; SMN2PDK1 | |
| SCHEMBL9940046 | 0.87 | NPC1 (0.49) | POLBNPC1RAB9ASMN1; SMN2PDK1 | |
| SCHEMBL11450804 | 0.87 | NPC1 (0.49) | POLBNPC1RAB9ASMN1; SMN2PDK1 | |
| SCHEMBL2499400 | 0.87 | NPC1 (0.49) | POLBNPC1RAB9ASMN1; SMN2PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903021-B1 | PROCESS FOR PRODUCTION OF FLUOROCOMPOUNDS | TOSOH F TECH INC (JP) | 2015-09-30 | — | — | EP | disclosed |
| CN-101151232-B | Process for production of fluorocompounds | TOSOH F TECH INC | 2011-07-13 | — | — | CN | disclosed |
| US-7615669-B2 | Process for producing fluoro-compounds | TOSOH F-TECH, INC. (JP) | 2009-11-10 | — | — | US | disclosed |
| US-20090030228-A1 | Process for producing fluoro-compounds | TOSOH F-TECH, INC. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1903021-A1 | PROCESS FOR PRODUCTION OF FLUOROCOMPOUNDS | Tosoh F-Tech, Inc. (JP) | 2008-03-26 | — | — | EP | disclosed |
| CN-101151232-A | Process for production of fluorocompounds | TOSOH F TECH INC (JP) | 2008-03-26 | — | — | CN | disclosed |
| EP-1465891-A4 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARM INC (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20050070719-A1 | Inhibitors of dipeptidyl peptidase iv | GUILFORD PHARMACEUTICALS | 2005-03-31 | — | — | US | disclosed |
| EP-1465891-A2 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057666-A2 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS (US) | 2003-07-17 | — | — | WO | disclosed |
| WO-2003057144-A2 | CHANGE INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS (US) | 2003-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070719-A1 | Inhibitors of dipeptidyl peptidase iv | DPP4, DPP3, DPP7 | POLB 3990/4885FKBP1A 2193/4885NPSR1 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.