Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | METAP1 | P53582 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952005 | 0.83 | KDM4E (0.68) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL11369441 | 0.82 | TGFBR1 (0.57) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL19916545 | 0.81 | NPC1 (0.48) | NPC1POLBSMN1; SMN2TGFBR1NQO2 | |
| SCHEMBL14063447 | 0.81 | KDM4E (0.66) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| Phenazine SCHEMBL25380403 | 0.81 | KDM4E (0.74) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL3210621 | 0.80 | KDM4E (0.53) | KDM4ENPC1LMNACCR1CCR5 | |
| SCHEMBL26260190 | 0.79 | KDM4E (0.57) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL4420314 | 0.79 | NPC1 (0.71) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL9838799 | 0.79 | ALDH1A1 (0.52) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB | |
| SCHEMBL31121089 | 0.79 | ALDH1A1 (0.52) | PIK3CDPIK3CAPI4KAPIK3CGPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124699-A1 | USE OF A MOLECULE AS SWITCHING ELEMENT | FORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |