⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967651 | 0.83 | — | — | |
| SCHEMBL3267732 | 0.81 | DNM1 (0.46) | — | |
| SCHEMBL7273338 | 0.79 | DNM1 (0.50) | — | |
| SCHEMBL5395578 | 0.79 | DNM1 (0.50) | — | |
| SCHEMBL7526104 | 0.79 | CA12 (0.42) | — | |
| SCHEMBL42469 | 0.77 | — | — | |
| SCHEMBL498779 | 0.77 | — | — | |
| SCHEMBL43187 | 0.75 | — | — | |
| SCHEMBL293544 | 0.74 | — | — | |
| SCHEMBL4156486 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | disclosed |
| US-20230390249-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-12-07 | — | — | US | disclosed |
| CN-115554294-A | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115477649-A | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115429798-A | 7-substituted 1-arylnaphthyridine-3-carboxamides and their use | 拜耳股份公司 | 2022-12-06 | — | — | CN | disclosed |
| US-20210244711-A1 | CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-08-12 | — | — | US | disclosed |
| EP-3512849-B1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | BAYER AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| US-11007180-B2 | Carbamoyloxymethyl triazole cyclohexyl acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-18 | — | — | US | disclosed |
| US-10927109-B2 | 7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-23 | — | — | US | disclosed |
| US-5310735-A | Carbapenem derivatives having antibiotic activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0505565-B1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5302711-A | Ester cleavage process for use with β-lactams | ELI LILLY AND COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0557035-A2 | An ester cleavage process for use with beta-lactams | ELI LILLY AND COMPANY (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0505565-A1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE. | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-09-30 | — | — | EP | disclosed |
| EP-0443883-A1 | Carbapenem derivatives having antibiotic activity, their preparation and their use | Sankyo Company Limited (JP) | 1991-08-28 | — | — | EP | disclosed |
| WO-1991009017-A1 | QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-27 | — | — | WO | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |