Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19288013 | 0.92 | EPHX2 (0.38) | CA12CA9CA2EPHX2TSHR | |
| SCHEMBL14617689 | 0.88 | ALDH1A1 (0.39) | CA12CA9CA2EPHX2TSHR | |
| SCHEMBL11412702 | 0.86 | CA12 (0.48) | CA12CA9CA2EPHX2TSHR | |
| SCHEMBL1618286 | 0.86 | CA12 (0.37) | CA12CA9CA2EPHX2TSHR | |
| SCHEMBL11631933 | 0.82 | EPHX2 (0.52) | CA12CA9EPHX2TSHRALDH1A1 | |
| SCHEMBL10816873 | 0.80 | EPHX2 (0.59) | EPHX2ALDH1A1CES2CES1KDM5A | |
| SCHEMBL22451059 | 0.80 | FDPS (0.35) | CA12CA9CA2EPHX2TSHR | |
| SCHEMBL42469 | 0.79 | — | — | |
| SCHEMBL498779 | 0.79 | — | — | |
| SCHEMBL42468 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873989-B1 | Process for the preparation of distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| EP-0849244-B1 | Process for the preparation of distyryl-biphenylic compounds | CIBA SC HOLDING AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-6031126-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| US-5969204-A | Process for the production of distyryl-biphenyl compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5952524-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| CN-1198435-A | Method for producing fluorescent whitening agent | CIBA GEIGY AG (CH) | 1998-11-11 | — | — | CN | disclosed |
| EP-0873988-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| EP-0873989-A2 | Process for the preparation of distyryl-biphenyl compounds | Ciba SC Holding AG (CH) | 1998-10-28 | — | — | EP | disclosed |
| EP-0849244-A1 | Process for the preparation of distyryl-biphenylic compounds | Ciba SC Holding AG (CH) | 1998-06-24 | — | — | EP | disclosed |
| US-5637763-A | Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N,N'-substituted ureas | CIBA-GEIGY CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5508402-A | Process for the preparation of N,N'-substituted ureas | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0552586-B1 | Process for the production of cyclopropylmethylketone | CIBA GEIGY AG (CH) | 1995-09-20 | — | — | EP | disclosed |
| CN-1027537-C | Improvements in or relating to carbemate derivatives | LILLY CO ELI (US) | 1995-02-01 | — | — | CN | disclosed |
| EP-0584043-A1 | Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N'N-substituted ureas | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |
| US-5254739-A | Heating a-acetylbutyrolactone in presence of a halide | CIBA-GEIGY CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0296864-B1 | PROCESS FOR PREPARING UREAS | DOWELANCO (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0552586-A1 | Process for the production of cyclopropylmethylketone | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4987233-A | Process for preparing herbicidal ureas and insecticidal carbamates and carbamate derivatives | ELI LILLY AND COMPANY (US) | 1991-01-22 | — | — | US | disclosed |
| CN-1030233-A | The improved method of preparation carbamate derivatives | LILLY CO ELI (US) | 1989-01-11 | — | — | CN | disclosed |
| EP-0296864-A2 | Process for preparing ureas | DOWELANCO (US) | 1988-12-28 | — | — | EP | disclosed |