Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 13/20 | 0.47 |
| ▸ | CDC25B | P30305 | 13/20 | 0.47 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247042 | 1.00 | PLA2G1B (0.52) | PLA2G1BINPP5DCDC25ACDC25BCYP8B1 | |
| SCHEMBL4247041 | 0.84 | PLA2G1B (0.60) | PLA2G1BINPP5DCDC25ACDC25BCYP8B1 | |
| SCHEMBL7832674 | 0.73 | CYP8B1 (0.63) | CDC25ACDC25BCYP8B1MEN1KMT2A | |
| SCHEMBL16226832 | 0.72 | INPP5D (0.57) | PLA2G1BINPP5DCDC25ACDC25BMEN1 | |
| SCHEMBL3447573 | 0.70 | CYP2D6 (0.65) | INPP5DCDC25ACDC25BMEN1USP2 | |
| SCHEMBL28408 | 0.70 | CYP2D6 (0.65) | INPP5DCDC25ACDC25BMEN1USP2 | |
| SCHEMBL9224303 | 0.70 | CYP2D6 (0.65) | INPP5DCDC25ACDC25BMEN1USP2 | |
| SCHEMBL133952 | 0.70 | CYP2D6 (0.65) | INPP5DCDC25ACDC25BMEN1USP2 | |
| SCHEMBL18541413 | 0.70 | INPP5D (0.73) | PLA2G1BINPP5DCDC25ACDC25BCYP8B1 | |
| Water SCHEMBL4949873 | 0.69 | CYP2D6 (0.64) | INPP5DCDC25ACDC25BMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946201-B2 | Methods for inhibiting TGF-β | SAINT LOUIS UNIVERSITY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20090062247-A1 | METHODS FOR INHIBITING TGF-beta | ST. LOUIS UNIVERSITY | 2009-03-05 | — | — | US | disclosed |