SCHEMBL4247111

SCHEMBL4247111

CC(C)COC(C)(C)OC(=O)C1C2C=CC(C2)C1C(=O)OC(C)(C)OCC(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
NPC1 O15118 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.36
HTT P42858 1/20 0.35
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28634176 0.80 ALDH1A1 (0.41) ALDH1A1RAB9APOLBLMNA
SCHEMBL3292755 0.77 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2POLBHTTLMNA
SCHEMBL1196057 0.77 ALDH1A1 (0.49) ALDH1A1NPC1TSHRRAB9ASMN1; SMN2
SCHEMBL1409756 0.75 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2POLBHTTLMNA
SCHEMBL13517735 0.72 ALDH1A1 (0.59) ALDH1A1NPC1TSHRRAB9ASMN1; SMN2
SCHEMBL3150000 0.69 POLB (0.51) ALDH1A1SMN1; SMN2POLBLMNA
SCHEMBL5838089 0.69 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2POLBHTTLMNA
SCHEMBL7723978 0.69 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2POLBHTTLMNA
SCHEMBL5837416 0.69 POLB (0.51) ALDH1A1SMN1; SMN2POLBLMNA
SCHEMBL5838085 0.69 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2POLBHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
WO-2025011754-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2025-01-16 WO disclosed
EP-4114825-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2024-11-20 EP disclosed
CN-113316744-B Oxime ester photoinitiators with special aroyl chromophores 巴斯夫欧洲公司 2024-07-30 CN disclosed
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2023-05-11 US disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
US-20220121113-A1 OXIME ESTER PHOTOINITIATORS HAVING A SPECIAL AROYL CHROMOPHORE BASF SE (DE) 2022-04-21 US disclosed
EP-3044208-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2021-12-22 EP disclosed
US-10793555-B2 Oxime ester photoinitiators BASF SE (DE) 2020-10-06 US disclosed
US-20180208583-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-07-26 US disclosed
US-9957258-B2 Oxime ester photoinitiators BASF SE (DE) 2018-05-01 US disclosed
US-20160214966-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2016-07-28 US disclosed
US-20090169736-A1 THERMOSETTING RESIN COMPOSITION, METHOD OF FORMING ANTIHALATION FILM OF SOLID-STATE IMAGING DEVICE, ANTIHALATION FILM FOR SOLID-STATE IMAGING DEVICES, AND SOLID-STATE IMAGING DEVICE JSR CORPORATION (JP) 2009-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793555-B2 Oxime ester photoinitiators NR2E3, OXER1, CBR3 ALDH1A1 929/4885NPC1 3823/4885TSHR 310/4885
US-20180208583-A1 OXIME ESTER PHOTOINITIATORS NR2E3, OXER1, CBR3 ALDH1A1 929/4885NPC1 3823/4885TSHR 310/4885
US-20160214966-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 ALDH1A1 854/4885NPC1 4754/4885TSHR 2377/4885
US-20230142648-A1 OXIME ESTER PHOTOINITIATORS OCIAD1, OCIAD2, OXER1 ALDH1A1 964/4885NPC1 4686/4885TSHR 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.