Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13370774 | 0.88 | HTR6 (0.58) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL9704151 | 0.84 | HTR6 (0.55) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL23409831 | 0.81 | HTR6 (0.51) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL21177167 | 0.81 | HTR6 (0.51) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL29788239 | 0.81 | HTR6 (0.51) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL30514817 | 0.81 | HTR6 (0.51) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL31352974 | 0.80 | HTR6 (0.77) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL11797291 | 0.80 | HTR6 (0.50) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL20314686 | 0.80 | HTR6 (0.50) | HTR6NFE2L2POLBHTT | |
| SCHEMBL28547097 | 0.80 | HTR6 (0.54) | HTR6SMN1; SMN2KMT2ATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1992612-A1 | 1-FLUORO-1,1-BIS(PHENYLSULFONYL)METHANE AND METHOD FOR PRODUCING SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | CYP2S1, ARSA, MSMO1 | HTR6 1149/4885PLCG1 1435/4885CA12 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.