Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791782 | 0.86 | EDNRA (0.46) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL13370774 | 0.84 | HTR6 (0.58) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL4247206 | 0.84 | HTR6 (0.58) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL28592916 | 0.80 | HTR6 (0.50) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL9740667 | 0.79 | HTR6 (0.49) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL23409831 | 0.78 | HTR6 (0.51) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL29788239 | 0.78 | HTR6 (0.51) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL30514817 | 0.78 | HTR6 (0.51) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL21177167 | 0.78 | HTR6 (0.51) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL1299047 | 0.78 | HTR6 (0.60) | HTR6CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |