Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201805 | 0.89 | KMT2A (0.53) | HSD17B10MAPK1KMT2AMAOBLMNA | |
| SCHEMBL6795273 | 0.84 | RARB (0.53) | HSD17B10KMT2AMEN1MAPTRARB | |
| SCHEMBL1290446 | 0.83 | TSHR (0.50) | HSD17B10KMT2AMAOBLMNAMAPT | |
| SCHEMBL17457887 | 0.81 | HSD17B10 (0.74) | HSD17B10KMT2ALMNAMMP12MMP13 | |
| SCHEMBL11424105 | 0.81 | HSD17B10 (0.74) | HSD17B10KMT2ALMNAMMP12MMP13 | |
| SCHEMBL10785469 | 0.79 | RARB (0.54) | KMT2AMEN1MAPTRARB | |
| SCHEMBL904232 | 0.78 | ALDH1A1 (0.43) | HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL1687902 | 0.78 | ALDH1A1 (0.46) | KMT2ALMNAL3MBTL1MEN1MAPT | |
| SCHEMBL27765863 | 0.78 | ESR1 (0.50) | HSD17B10KMT2ALMNAL3MBTL1 | |
| SCHEMBL2731049 | 0.77 | THRA (0.59) | THRATHRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015107548-A1 | IMPROVED FINGOLIMOD PROCESS | EMCURE PHARMACEUTICALS LIMITED (IN) | 2015-07-23 | — | — | WO | disclosed |
| WO-2012056458-A2 | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF FINGOLIMOD | MAPI PHARMA LTD. (IL) | 2012-05-03 | — | — | WO | disclosed |