SCHEMBL4247253

SCHEMBL4247253

CCCCCOC(=O)c1cc(=O)c2cccc(N)c2o1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.59
ALDH1A1 P00352 6/20 0.51
KDM4E B2RXH2 3/20 0.51
HSD17B10 Q99714 2/20 0.51
POLB P06746 1/20 0.51
MAPT P10636 2/20 0.49
TSHR P16473 4/20 0.45
MAPK1 P28482 2/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
LMNA P02545 2/20 0.45
AKR1B1 P15121 2/20 0.44
MMP1 P03956 1/20 0.44
MMP9 P14780 1/20 0.44
MMP12 P39900 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ATM Q13315 1/20 0.43
GPR35 Q9HC97 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4256564 0.99 MAOB (0.58) MAOBALDH1A1KDM4EHSD17B10POLB
SCHEMBL4252681 0.96 MAOB (0.60) MAOBALDH1A1KDM4EHSD17B10POLB
SCHEMBL4250588 0.93 MAOB (0.69) MAOBALDH1A1KDM4EHSD17B10POLB
SCHEMBL4254725 0.88 AKR1B1 (0.57) MAOBALDH1A1KDM4EHSD17B10MAPT
SCHEMBL4253612 0.84 MAOB (0.57) MAOBALDH1A1KDM4EHSD17B10POLB
SCHEMBL27635896 0.84 MAOB (0.83) MAOBALDH1A1KDM4EMAPTTSHR
SCHEMBL4251266 0.83 MAOB (0.56) MAOBALDH1A1KDM4EHSD17B10POLB
SCHEMBL4252013 0.83 MAOB (0.49) MAOBALDH1A1KDM4EMAPTTSHR
SCHEMBL4251271 0.82 GPR35 (0.62) MAOBALDH1A1KDM4EMAPTTSHR
SCHEMBL4258050 0.81 GPR35 (0.61) MAOBALDH1A1KDM4EHSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101497571-B Process for producing chromone compound SUMITOMO CO LTD 2012-07-04 CN disclosed
CN-1911896-B Process for producing benzopyrone compound SUMITOMO CHEMICAL CO 2010-09-15 CN disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
CN-101497571-A Process for producing chromone compound SUMITOMO CHEMICAL CO (JP) 2009-08-05 CN disclosed
CN-100509751-C Process for producing benzopyranone compound SUMITOMO CHEMICAL CO (JP) 2009-07-08 CN disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
CN-1911896-A Process for producing chromone compound SUMITOMO CHEMICAL CO (JP) 2007-02-14 CN disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
CN-1649824-A Process for producing benzopyranone compound SUMITOMO CHEMICAL CO (JP) 2005-08-03 CN disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL MAOB 476/4885ALDH1A1 3157/4885KDM4E 978/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL MAOB 476/4885ALDH1A1 3157/4885KDM4E 978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.