⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060050 | 1.00 | — | — | |
| SCHEMBL419252 | 0.80 | — | — | |
| SCHEMBL419251 | 0.80 | — | — | |
| SCHEMBL424063 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL424064 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL426320 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL426321 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL424144 | 0.76 | — | — | |
| SCHEMBL425614 | 0.73 | — | — | |
| SCHEMBL425613 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385904-A | Green synthesis method of thiamethoxam | 内蒙古同创高科化学有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-111217765-A | Synthesis process of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine | 宁夏东吴农化股份有限公司 | 2020-06-02 | — | — | CN | claimed |
| EP-0850231-B1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-02 | — | — | EP | claimed |
| US-6187927-B1 | REACTING 2-CHLOROALLYLFORMAMIDE WITH DEHYDRATING, HALOGENATING, AND SULFURIZING AGENTS | NOVARTIS CROP PROTECTION, INC. | 2001-02-13 | — | — | US | claimed |
| CN-115872944-B | Synthesis method of thiamethoxam intermediate | 长青(湖北)生物科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115385904-A | Green synthesis method of thiamethoxam | 内蒙古同创高科化学有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-11459359-B2 | Proteins toxic to hemipteran insect species | MONSANTO TECHNOLOGY LLC (US) | 2022-10-04 | — | — | US | disclosed |
| CN-111315743-A | Method for preparing thiamethoxam | 江苏龙灯化学有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111217765-A | Synthesis process of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine | 宁夏东吴农化股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-111217765-A | Synthesis process of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine | 宁夏东吴农化股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-111217765-A | Synthesis process of 3-methyl-4-nitroiminoperhydro-1,3,5-oxadiazine | 宁夏东吴农化股份有限公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-3480196-A1 | PROCESS FOR THE PREPARATION OF THIAMETHOXAM | Jiangsu Rotam Chemistry Co., Ltd (CN) | 2019-05-08 | — | — | EP | disclosed |
| EP-0958286-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Novartis AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| EP-0946531-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Novartis AG (CH) | 1999-10-06 | — | — | EP | disclosed |
| US-5852012-A | Oxadiazine derivatives | NOVARTIS CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| WO-1998032747-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-07-30 | — | — | WO | disclosed |
| EP-0850231-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | Novartis AG (CH) | 1998-07-01 | — | — | EP | disclosed |
| WO-1998027074-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-06-25 | — | — | WO | disclosed |
| WO-1997010226-A1 | PROCESS FOR PREPARING A 2-CHLORO-5-CHLOROMETHYL-THIAZOLE COMPOUND | NOVARTIS AG (CH) | 1997-03-20 | — | — | WO | disclosed |
| EP-0580553-A2 | Oxadiazine derivatives | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |