SCHEMBL4247610

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5617734	0.88	TLR7 (0.42)	TLR7TLR8
	SCHEMBL4245979	0.87	TLR7 (0.44)	TLR7TLR8MAPT
	SCHEMBL4241460	0.85	CHEK2 (0.46)	TLR7TLR8KDR
	SCHEMBL4245395	0.85	TLR7 (0.41)	TLR7TLR8POLBALDH1A1
	SCHEMBL4064140	0.82	TLR7 (0.44)	TLR7TLR8
	SCHEMBL5618272	0.78	TLR7 (0.55)	TLR7TLR8
	SCHEMBL5617730	0.78	TLR7 (0.43)	TLR7TLR8ALDH1A1TSHR
	SCHEMBL4243750	0.77	TLR7 (0.55)	TLR7TLR8POLBLMNA
	SCHEMBL4244345	0.76	TLR7 (0.53)	TLR7TLR8
	SCHEMBL4240961	0.75	TLR7 (0.48)	TLR7TLR8MAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.