Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251806 | 0.89 | KDM4E (0.59) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5448947 | 0.87 | KDM4E (0.66) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5443445 | 0.80 | KDM4E (0.56) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4070699 | 0.79 | ALDH1A1 (0.55) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL23149478 | 0.78 | GUSB (0.61) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL30966039 | 0.78 | GUSB (0.61) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4075906 | 0.78 | PKM (0.58) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4081693 | 0.78 | GUSB (0.60) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4077900 | 0.78 | KDM4E (0.55) | KDM4EHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4073364 | 0.78 | ALDH1A1 (0.56) | KDM4EHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040711-A2 | 2-OXO-1,2-DIHYDROQUINOLINE DERIVATIVES, COMPOSITIONS, AND USES THEREOF AS ANTIPROLIFERATIVE AGENTS | Amphora Discovery Corporation (US) | 2009-04-01 | — | — | EP | claimed |
| WO-2007136592-A2 | 2-0X0-L,2-DIHYDR0QUIN0LINE DERIVATIVES, COMPOSITIONS, AND USES THEREOF AS ANTIPROLIFERATIVE AGENTS | AMPHORA DISCOVERY CORPORATION (US) | 2007-11-29 | — | — | WO | claimed |