Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247793 | 1.00 | HTR1A (0.55) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4244762 | 1.00 | HTR1A (0.55) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4244759 | 1.00 | HTR1A (0.55) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4239956 | 0.98 | HTR1A (0.53) | HTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4239961 | 0.98 | HTR1A (0.53) | HTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4245064 | 0.80 | SMN1; SMN2 (0.58) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4245062 | 0.80 | SMN1; SMN2 (0.58) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4243784 | 0.79 | SMN1; SMN2 (0.49) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4247498 | 0.79 | SMN1; SMN2 (0.49) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4243780 | 0.79 | HTR1A (0.49) | HTR1ASMN1; SMN2KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036455-A1 | ARYLPIPERAZINE DERIVATIVE AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | CEPA SCHWARZ PHARMA, S.L. (ES) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036455-A1 | ARYLPIPERAZINE DERIVATIVE AND USE THEREOF AS 5-HT1A RECEPTOR LIGANDS | HTR1A, HTR5A, HTR2C | HTR1A 1/4885SMN1; SMN2 1400/4885KDM4E 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.