Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667666 | 0.82 | TLR7 (0.72) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL1486483 | 0.80 | TLR7 (0.67) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL1486556 | 0.74 | NMT1 (0.46) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL1486540 | 0.73 | TLR7 (0.55) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL1486435 | 0.72 | TLR7 (0.70) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL19522764 | 0.72 | TLR7 (0.59) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL15911858 | 0.72 | TLR7 (0.67) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL1486437 | 0.72 | HRH3 (0.44) | ALOX5CYP3A4HRH3GRM4DYRK1A | |
| SCHEMBL3864168 | 0.72 | TLR7 (0.73) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL1486582 | 0.71 | LMNA (0.46) | TLR7PDE4DLMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-A4 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1658076-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005020999-A1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |