(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL424799

O=C1OC(=O)c2ccccc21.O=C1OC(=O)c2ccccc21.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.64
HTR6 P50406 3/20 0.64
ALOX15 P16050 1/20 0.64
TYMS P04818 3/20 0.45
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
LOX P28300 2/20 0.43
TSHR P16473 2/20 0.43
PKM P14618 1/20 0.43
MAOA P21397 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
CDC25B P30305 1/20 0.42
MAPT P10636 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4959613 0.86 HTR6 (0.52) TDP1HTR6ALOX15TYMSALDH1A1
SCHEMBL19818355 0.83 TDP1 (0.93) TDP1ALOX15TYMSALDH1A1KDM4E
Phthalic Anhydride SCHEMBL5679433 0.83 TDP1 (0.93) TDP1ALOX15TYMSALDH1A1KDM4E
Phthalic Anhydride SCHEMBL29356227 0.80 TDP1 (1.00) TDP1ALOX15TYMSALDH1A1KDM4E
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.80 HTR6 (1.00) TDP1HTR6ALDH1A1TSHRPKM
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.80 HTR6 (1.00) TDP1HTR6ALDH1A1TSHRPKM
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.80 HTR6 (1.00) TDP1HTR6ALDH1A1TSHRPKM
Phthalic Anhydride SCHEMBL380499 0.80 TDP1 (1.00) TDP1ALOX15TYMSALDH1A1KDM4E
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.80 HTR6 (1.00) TDP1HTR6ALDH1A1TSHRPKM
(Phenylsulfonyl)Benzene SCHEMBL30255 0.80 HTR6 (1.00) TDP1HTR6ALDH1A1TSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951815-B1 FLAME RESISTANT POLYMER BLENDS SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-05-24 EP disclosed
EP-2707434-B1 SILICONE POLYETHERIMIDE COPOLYMERS SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-06-22 EP disclosed
EP-2596049-B1 SILICONE POLYIMIDE COMPOSITIONS WITH IMPROVE FLAME RETARDANCE SABIC INNOVATIVE PLASTICS IP (NL) 2014-08-20 EP disclosed
EP-2707434-A1 SILICONE POLYETHERIMIDE COPOLYMERS SABIC Innovative Plastics IP B.V. (NL) 2014-03-19 EP disclosed
EP-2596049-A1 SILICONE POLYIMIDE COMPOSITIONS WITH IMPROVE FLAME RETARDANCE SABIC Innovative Plastics IP B.V. (NL) 2013-05-29 EP disclosed
US-8349933-B2 Silicone polyimide compositions with improved flame retardance SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-01-08 US disclosed
WO-2012154966-A1 SILICONE POLYETHERIMIDE COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-11-15 WO disclosed
US-20120285721-A1 SILICONE POLYETHERIMIDE COPOLYMERS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2012-11-15 US disclosed
US-20120021153-A1 Silicone Polyimide Compositions With Improved Flame Retardance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2012-01-26 US disclosed
WO-2012012643-A1 SILICONE POLYIMIDE COMPOSITIONS WITH IMPROVE FLAME RETARDANCE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-26 WO disclosed
EP-2366740-A2 Flame resistant polymer blends SABIC Innovative Plastics IP B.V. (NL) 2011-09-21 EP disclosed
US-7652107-B2 Blends of siloxane copolymers with polyaryl esters or polyaryl ester carbonates containing linkages derived from resorcinol, show improved flame resistance SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-26 US disclosed
EP-1951815-A1 FLAME RESISTANT POLYMER BLENDS General Electric Company (US) 2008-08-06 EP disclosed
WO-2007053307-A1 FLAME RESISTANT POLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 2007-05-10 WO disclosed
US-20070100088-A1 Flame resistant polymer blends GENERAL ELECTRIC COMPANY (US) 2007-05-03 US disclosed