Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 8/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252650 | 0.97 | GNRHR (0.36) | KMT2AL3MBTL1GNRHRKIF11BRD4 | |
| SCHEMBL4248792 | 0.86 | GNRHR (0.38) | L3MBTL1GNRHRKIF11BRD4SIGMAR1 | |
| SCHEMBL4248789 | 0.86 | GNRHR (0.38) | L3MBTL1GNRHRKIF11BRD4SIGMAR1 | |
| SCHEMBL4252736 | 0.86 | KIF11 (0.40) | GNRHRKIF11BRD4SIGMAR1 | |
| SCHEMBL4252742 | 0.86 | KIF11 (0.40) | GNRHRKIF11BRD4SIGMAR1 | |
| SCHEMBL4252319 | 0.84 | BRD4 (0.39) | L3MBTL1GNRHRKIF11BRD4 | |
| SCHEMBL4252323 | 0.84 | BRD4 (0.39) | L3MBTL1GNRHRKIF11BRD4 | |
| SCHEMBL4250123 | 0.84 | KIF11 (0.39) | GNRHRKIF11BRD4SIGMAR1 | |
| SCHEMBL4250128 | 0.84 | KIF11 (0.39) | GNRHRKIF11BRD4SIGMAR1 | |
| SCHEMBL4250470 | 0.81 | GNRHR (0.39) | KMT2AL3MBTL1GNRHRKIF11BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035426-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007144384-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2007-12-21 | — | — | WO | disclosed |