Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824467 | 0.85 | PARP10 (0.54) | PARP10NPC1PLK1NPSR1PLA2G4B | |
| SCHEMBL4246590 | 0.80 | CES2 (0.55) | PARP10PLK1NPSR1KMT2AALDH1A1 | |
| SCHEMBL13945433 | 0.80 | PARP10 (0.61) | PARP10NPC1PLK1NPSR1PLA2G4B | |
| SCHEMBL11372020 | 0.79 | CA1 (0.58) | NPC1NPSR1KMT2AALDH1A1RAB9A | |
| SCHEMBL3393415 | 0.79 | TP53 (0.36) | ALDH1A1HPGDLMNAHTTMAPT | |
| SCHEMBL6997144 | 0.77 | ELANE (0.53) | NPC1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL7990900 | 0.76 | PARP10 (0.56) | PARP10NPC1PLK1NPSR1PLA2G4B | |
| SCHEMBL1367365 | 0.75 | PARP10 (0.70) | PARP10NPC1PLK1NPSR1PLA2G4B | |
| SCHEMBL845348 | 0.75 | NPSR1 (0.79) | PARP10NPC1PLK1NPSR1PLA2G4B | |
| SCHEMBL7985087 | 0.75 | PARP10 (0.54) | PARP10NPC1PLK1NPSR1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473700-B2 | 1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (KR) | 2009-01-06 | — | — | US | disclosed |
| US-20060074118-A1 | 1, 2, 4 - Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |
| EP-1565447-A4 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORP (KR) | 2005-11-16 | — | — | EP | disclosed |
| EP-1565447-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004048347-A1 | 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074118-A1 | 1, 2, 4 - Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CYP4B1, CYP3A4, CYP3A5 | PARP10 2562/4885NPC1 361/4885PLK1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.