Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 3/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM6A | O15550 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 1/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20893273 | 0.90 | COMT (0.81) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL9206381 | 0.81 | COMT (0.68) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL29255918 | 0.80 | COMT (0.66) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL28783650 | 0.80 | COMT (0.66) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL13485863 | 0.79 | COMT (0.65) | COMTNOTUMKDM4ESMN1; SMN2KDM6A | |
| SCHEMBL11626746 | 0.79 | COMT (0.65) | COMTNOTUMKDM4ESMN1; SMN2CYP2C9 | |
| Hydrochloric Acid SCHEMBL30701792 | 0.78 | COMT (0.64) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL17567295 | 0.78 | COMT (0.67) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL16415821 | 0.77 | COMT (0.62) | COMTNOTUMKDM4ESMN1; SMN2TP53 | |
| SCHEMBL12492420 | 0.77 | COMT (0.62) | COMTKDM4EHTTKDM6AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2775839-B1 | METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | UNIV CALIFORNIA (US) | 2023-12-06 | — | — | EP | disclosed |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-12 | — | — | US | disclosed |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-12 | — | — | US | disclosed |
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-04-11 | — | — | US | disclosed |
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-04-11 | — | — | US | disclosed |
| WO-2017156194-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156194-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-14 | — | — | WO | disclosed |
| JP-2009234959-A | SKIN-WHITENING AGENT COMPRISING 3-HYDROXY-2-METHYL-1-PHENYL-4-PYRIDINONE OR DERIVATIVE OF THE SAME, SKIN-WHITENING PREPARATION FOR EXTERNAL USE, AND COSMETIC CONTAINING THE SKIN-WHITENING AGENT | PIAS ARISE KK | 2009-10-15 | — | — | JP | disclosed |
| US-5814614-A | Substituted glucose compounds for toxic metal ion removal from the body | KRUCK THEO P A (CA) | 1998-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | POLRMT, RNASE1, POLM | COMT 2088/4885NOTUM 2276/4885KDM4E 3340/4885 |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | POLRMT, RNASE1, POLM | COMT 2088/4885NOTUM 2276/4885KDM4E 3340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.