Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245546 | 0.95 | KCNH2 (0.44) | CACNA1GLMNAKMT2AMEN1 | |
| SCHEMBL4247009 | 0.89 | CACNA1G (0.53) | CACNA1GLMNANPSR1P2RX7HTT | |
| SCHEMBL4245649 | 0.86 | CACNA1G (0.41) | CACNA1G | |
| SCHEMBL4256059 | 0.85 | CACNA1G (0.50) | CACNA1GP2RX7 | |
| SCHEMBL4245578 | 0.84 | CACNA1G (0.49) | CACNA1GLMNAKMT2AMEN1MAPK1 | |
| SCHEMBL4248063 | 0.81 | CACNA1G (0.39) | CACNA1GLMNANPSR1ALDH1A1MAPT | |
| SCHEMBL4249535 | 0.81 | CACNA1G (0.45) | CACNA1GLMNANPSR1P2RX7HTT | |
| SCHEMBL4245552 | 0.81 | HTR6 (0.47) | CACNA1G | |
| SCHEMBL4249379 | 0.80 | CACNA1G (0.45) | CACNA1GLMNANPSR1KMT2AMEN1 | |
| SCHEMBL4247776 | 0.80 | HRH1 (0.46) | CACNA1GLMNAKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757590-B1 | Piperazinylalkylpyrazole derivatives useful as selective T-type calcium channel blockers and preparation method thereof | KOREA INST SCI & TECH (KR) | 2009-12-02 | — | — | EP | claimed |