Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KMO | O15229 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | CCNC | P24863 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104146 | 0.94 | HPGD (0.69) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL4252992 | 0.92 | L3MBTL3 (0.62) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL28504587 | 0.87 | HPGD (0.72) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL4248924 | 0.87 | HPGD (0.73) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL23440313 | 0.86 | HPGD (0.71) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL18397598 | 0.86 | HPGD (0.71) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL29699833 | 0.86 | HPGD (0.71) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL6614562 | 0.85 | HPGD (1.00) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL3456729 | 0.84 | HPGD (0.96) | HPGDMAPK1POLBMEN1KMT2A | |
| SCHEMBL3454812 | 0.84 | HPGD (0.96) | HPGDMAPK1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016907-B | Amide compound, compositions and application thereof | EVOTEC GMBH (DE) | 2016-11-30 | — | — | CN | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| EP-1960367-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067836-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | HPGD 13/4885MAPK1 3943/4885POLB 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.