Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178 | 1.00 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL30147 | 1.00 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL12584889 | 1.00 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL31588 | 1.00 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL18832827 | 1.00 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL30366682 | 0.97 | TDP1 (0.43) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| Hydrochloric Acid SCHEMBL10627881 | 0.95 | TDP1 (0.41) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL10627887 | 0.90 | TDP1 (0.38) | TDP1CYP3A4ESR1ESR2 | |
| SCHEMBL14713495 | 0.89 | TDP1 (0.41) | TDP1CYP3A4ESR1ESR2TAAR1 | |
| SCHEMBL18294158 | 0.89 | TDP1 (0.41) | TDP1CYP3A4ESR1ESR2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556294-B2 | Magnetic particle-polymer hybrid materials with functionalized polymers derived from norbornenyl reagents | THE UNIVERSITY OF KANSAS (US) | 2017-01-31 | — | — | US | disclosed |
| US-7973198-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2011-07-05 | — | — | US | disclosed |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1992612-A1 | 1-FLUORO-1,1-BIS(PHENYLSULFONYL)METHANE AND METHOD FOR PRODUCING SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2008-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | HMOX1, HMOX2, CBR1 | TDP1 4870/4885CYP3A4 428/4885ESR1 3106/4885 |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | CYP2S1, ARSA, MSMO1 | TDP1 3003/4885CYP3A4 148/4885ESR1 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.