Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29681615 | 0.84 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL1706646 | 0.84 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL21686843 | 0.82 | LMNA (0.57) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| Hydrochloric Acid SCHEMBL21633576 | 0.80 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| Hydrochloric Acid SCHEMBL30763411 | 0.80 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL1706579 | 0.80 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL5630873 | 0.80 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL13066644 | 0.80 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL23083127 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL25541313 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2APRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049494-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008008310-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-17 | — | — | WO | claimed |
| EP-1255735-A2 | PYRIDINE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056990-A2 | PYRIDINE DERIVATES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2001-08-09 | — | — | WO | claimed |
| EP-2049494-A2 | TYROSINE KINASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008008310-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-17 | — | — | WO | disclosed |