Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250191 | 0.89 | CA2 (0.46) | HTTKCNH2TSHRLMNACYP2D6 | |
| SCHEMBL4535932 | 0.87 | KCNH2 (0.52) | HTTKCNH2TSHRLMNACYP2D6 | |
| SCHEMBL4246252 | 0.87 | KCNH2 (0.52) | HTTKCNH2TSHRLMNACYP2D6 | |
| SCHEMBL4246458 | 0.87 | KCNH2 (0.52) | HTTKCNH2TSHRLMNACYP2D6 | |
| SCHEMBL9500242 | 0.82 | LMNA (0.56) | HTTKCNH2TSHRLMNACYP2D6 | |
| Tetrabuthylammonium SCHEMBL9237587 | 0.80 | LMNA (0.68) | HTTKCNH2TSHRLMNACYP2D6 | |
| SCHEMBL11059907 | 0.79 | CA2 (0.66) | HTTKCNH2TSHRLMNACYP2D6 | |
| SCHEMBL3853262 | 0.79 | CA2 (0.66) | HTTKCNH2TSHRLMNACYP2D6 | |
| Lithium Ion SCHEMBL11715222 | 0.79 | CA2 (0.66) | HTTKCNH2TSHRLMNACYP2D6 | |
| Potassium Ion SCHEMBL282773 | 0.79 | CA2 (0.66) | HTTKCNH2TSHRLMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149668-A1 | Method for Producing Sodium Chloride-Free Ammonium Nitriles | CLARIANT INTERNATIONAL, LTD. (CH) | 2009-06-11 | — | — | US | disclosed |
| EP-2001836-A1 | IMPROVED METHOD FOR PRODUCING SODIUM CHLORIDE-FREE AMMONIUM NITRILES | CLARIANT INTERNATIONAL LTD. (CH) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007110163-A1 | IMPROVED METHOD FOR PRODUCING SODIUM CHLORIDE-FREE AMMONIUM NITRILES | CLARIANT INTERNATIONAL LTD (CH) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149668-A1 | Method for Producing Sodium Chloride-Free Ammonium Nitriles | CBR3, CBR1, AKR1C3 | HTT 2436/4885KCNH2 161/4885TSHR 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.