SCHEMBL74245

SCHEMBL74245

CCCN=Cc1ccccn1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.52
MAOA P21397 2/20 0.50
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
ATM Q13315 1/20 0.48
TOP2A P11388 2/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
G6PC1 P35575 1/20 0.46
ALDH1A1 P00352 2/20 0.46
PKM P14618 1/20 0.46
USP2 O75604 1/20 0.46
MAOB P27338 1/20 0.45
CTH P32929 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10308820 1.00 NR4A1 (0.52) NR4A1MAOAKMT2AMEN1NPC1
Bromide SCHEMBL4891392 0.96 NR4A1 (0.49) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL6334411 0.89 CYP1A2 (0.51) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL9261403 0.89 CYP1A2 (0.51) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL4250239 0.88 NR4A1 (0.59) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL4250235 0.88 NR4A1 (0.59) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL832503 0.88 CYP1A2 (0.53) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL832504 0.88 CYP1A2 (0.53) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL342149 0.86 CYP1A2 (0.56) NR4A1MAOAKMT2AMEN1NPC1
SCHEMBL10321022 0.86 CYP1A2 (0.56) NR4A1MAOAKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399450-A1 PREPARATION OF NON-POLAR-POLAR BLOCK COPOLYMERS VIA VINYL-TERMINATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-12-14 US claimed
EP-4244263-A1 PREPARATION OF NON-POLAR-POLAR BLOCK COPOLYMERS VIA VINYL-TERMINATED POLYOLEFINS Dow Global Technologies LLC (US) 2023-09-20 EP claimed
WO-2022103803-A1 PREPARATION OF NON-POLAR–POLAR BLOCK COPOLYMERS VIA VINYL-TERMINATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-05-19 WO claimed
US-11267831-B2 EF-Tu-binding metal-containing antibiotic RUHR-UNIVERSITAET BOCHUM (DE) 2022-03-08 US claimed
US-20200199162-A1 EF-TU-BINDING METAL-CONTAINING ANTIBIOTIC RUHR-UNIVERSITAET BOCHUM (DE) 2020-06-25 US claimed
EP-3649140-A1 EF-TU-BINDING ANTIBIOTIC CONTAINING METAL Ruhr-Universität Bochum (DE) 2020-05-13 EP claimed
CN-106872418-B Detect fluorescence probe system, probe synthesis and the application of phosphorylated protein 中国科学院大连化学物理研究所 2019-04-09 CN claimed
WO-2019007664-A1 EF-TU-BINDING ANTIBIOTIC CONTAINING METAL RUHR-UNIVERSITäT BOCHUM (DE) 2019-01-10 WO claimed
CN-106872418-A Detect fluorescence probe system, probe synthesis and the application of phosphorylated protein 中国科学院大连化学物理研究所 2017-06-20 CN claimed
CN-104193923-B Hydrophobic/oleophobic fluorosilicone triblock polymer and preparation method thereof 陕西省石油化工研究设计院 2017-01-18 CN claimed
US-8236466-B2 Photochromic materials incorporated in polymer backbone XEROX CORPORATION (US) 2012-08-07 US claimed
US-20110082035-A1 PHOTOCHROMIC MATERIALS INCORPORATED IN POLYMER BACKBONE XEROX CORPORATION (US) 2011-04-07 US claimed
EP-2161291-A2 Polymer Warwick Effect Polymers Limited (GB) 2010-03-10 EP claimed
EP-1646661-B1 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUNG OBTAINED THEREFROM WARWICK EFFECT POLYMERS LTD (GB) 2009-04-01 EP claimed
US-20080300348-A1 Polymer WARWICK EFFECT POLYMERS LIMITED 2008-12-04 US claimed
EP-1996629-A2 POLYMERS Warwick Effect Polymers Ltd. (GB) 2008-12-03 EP claimed
WO-2007104948-A2 POLYMERS WARWICK EFFECT POLYMERS LTD. (GB) 2007-09-20 WO claimed
JP-2007516302-A 2007-06-21 JP claimed
EP-1646661-A2 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUNG OBTAINED THEREFROM Warwick Effect Polymers Limited (GB) 2006-04-19 EP claimed
WO-2004113394-A2 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUGS OBTAINED THEREFROM WARWICK EFFECT POLYMERS LIMITED (GB) 2004-12-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200199162-A1 EF-TU-BINDING METAL-CONTAINING ANTIBIOTIC EFTUD2, MRPL21, LEF1 NR4A1 415/4885MAOA 1872/4885KMT2A 2632/4885
US-11267831-B2 EF-Tu-binding metal-containing antibiotic EFTUD2, MRPL21, LEF1 NR4A1 415/4885MAOA 1872/4885KMT2A 2632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.