Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529579 | 0.73 | GAA (0.42) | GAASMN1; SMN2ALOX15KMT2AL3MBTL1 | |
| SCHEMBL13939995 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL16978992 | 0.69 | — | — | |
| SCHEMBL24235272 | 0.67 | — | — | |
| SCHEMBL10207376 | 0.66 | TSHR (0.41) | — | |
| SCHEMBL20749854 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL11919130 | 0.65 | — | — | |
| SCHEMBL24235263 | 0.65 | — | — | |
| SCHEMBL18458997 | 0.65 | — | — | |
| SCHEMBL26004263 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608630-B2 | Prepared by extracting fungi Marasmius androsaceus L.es Fr with an organic solvent, an aqueous organic solvent or water, and concentrating the obtained extractive; use in treatment of cardiovascular disorders | HAINAN YANGPU NEW SPECIAL PHARMACEUTICAL CO., LTD. (CN) | 2009-10-27 | — | — | US | claimed |
| US-20090253742-A1 | MARASMIUS ANDROSACEUS L.ES FR EXTRACT, PIPERIDONE DERIVATIVE, AND THEIR USE FOR THE PREPARATION OF ANTIHYPERTENSIVES | HAINAN YANGPU NEW SPECIAL PHARMACEUTICAL CO., LTD. (CN) | 2009-10-08 | — | — | US | claimed |
| US-7608630-B2 | Prepared by extracting fungi Marasmius androsaceus L.es Fr with an organic solvent, an aqueous organic solvent or water, and concentrating the obtained extractive; use in treatment of cardiovascular disorders | HAINAN YANGPU NEW SPECIAL PHARMACEUTICAL CO., LTD. (CN) | 2009-10-27 | — | — | US | disclosed |
| US-20090253742-A1 | MARASMIUS ANDROSACEUS L.ES FR EXTRACT, PIPERIDONE DERIVATIVE, AND THEIR USE FOR THE PREPARATION OF ANTIHYPERTENSIVES | HAINAN YANGPU NEW SPECIAL PHARMACEUTICAL CO., LTD. (CN) | 2009-10-08 | — | — | US | disclosed |
| US-20070160625-A1 | Marasmius androsaceus l.es fr extract, piperidone derivative, and their use for the preparation of antihypertensives | HAINAN YANGPU NEW SPECIAL PHARMACEUTICAL CO., LTD. (CN) | 2007-07-12 | — | — | US | disclosed |
| EP-1710235-A1 | EXTRACTS OF MARASMINS ANDROSACEUS L.ES, PIPERDINONE DERIVATIVES AND THE USE AS ANTIHYPERTENSIVE AGENTS | Beijing Tuolin Medicine Science and Technology Co., Ltd. (CN) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253742-A1 | MARASMIUS ANDROSACEUS L.ES FR EXTRACT, PIPERIDONE DERIVATIVE, AND THEIR USE FOR THE PREPARATION OF ANTIHYPERTENSIVES | REN, PTGIS, EDNRA | GAA 3835/4885RAB9A 2702/4885SMN1; SMN2 2532/4885 |
| US-20070160625-A1 | Marasmius androsaceus l.es fr extract, piperidone derivative, and their use for the preparation of antihypertensives | REN, PTGIS, EDNRA | GAA 3835/4885RAB9A 2702/4885SMN1; SMN2 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.