Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592656 | 0.77 | NAPRT (0.44) | NAPRTMAPTKDM4EGAARAB9A | |
| SCHEMBL7936000 | 0.72 | LMNA (0.46) | NAPRTMAPTKDM4EGAARAB9A | |
| SCHEMBL2359714 | 0.72 | — | — | |
| SCHEMBL10866718 | 0.72 | NAPRT (0.33) | NAPRTMAPTKDM4EGAARAB9A | |
| SCHEMBL9978306 | 0.71 | — | — | |
| SCHEMBL6159526 | 0.71 | — | — | |
| SCHEMBL2789316 | 0.71 | PTGS2 (0.42) | NAPRTMAPTKDM4EGAATSHR | |
| SCHEMBL11387979 | 0.71 | NAPRT (0.39) | NAPRTMAPTKDM4EGAACYP2C19 | |
| SCHEMBL28379607 | 0.70 | GRIN2D (0.33) | NAPRTMAPTKDM4EGAARAB9A | |
| SCHEMBL12833352 | 0.70 | CYP1A2 (0.57) | MAPTKDM4ECYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170176470-A1 | DETECTION OF CARBOXYALKYLPYRROLE OR PENTYLPYRROLE ETHANOLAMINE PHOSPHOLIPIDS | UNIV CASE WESTERN RESERVE (US) | 2017-06-22 | — | — | US | disclosed |
| US-7560257-B2 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080160505-A1 | DIAGNOSTIC METHODS FOR AGE RELATED MACULAR DEGENERATION | THE CLEVELAND CLINIC FOUNDATION | 2008-07-03 | — | — | US | disclosed |
| US-7341839-B2 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-20070072241-A1 | diagnosing age-related macular degeneration comprising determining the level of anti-2-( omega -carboxyethyl) pyrrole (CEP) antibodies in a bodily fluid obtained from the test subject | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-03-29 | — | — | US | disclosed |
| US-7172874-B2 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040265924-A1 | Diagnostic methods for age related macular degeneration | THE CLEVELAND CLINIC FOUNDATION | 2004-12-30 | — | — | US | disclosed |
| WO-1997020203-A1 | NOVEL MEMBRANES AND MEMBRANE DNA/RNA SENSORS | SCHALKHAMMER THOMAS (AT) | 1997-06-05 | — | — | WO | disclosed |