Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779564 | 1.00 | PTPN1 (0.40) | PTPN1HTTSMN1; SMN2APPHSP90AA1 | |
| SCHEMBL4253743 | 0.84 | APP (0.37) | PTPN1HTTSMN1; SMN2APPHSP90AA1 | |
| SCHEMBL4254656 | 0.81 | PTPN1 (0.56) | PTPN1HSP90AA1XDHNPC1MGAM | |
| SCHEMBL4251925 | 0.71 | PTPN1 (0.57) | PTPN1HSP90AA1XDHPTGS1PTGS2 | |
| SCHEMBL23861462 | 0.70 | CDK4 (0.38) | APPHSP90AA1ALDH1A1HPGDSIRT1 | |
| SCHEMBL7263829 | 0.68 | SIRT2 (0.38) | HTTSMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL364008 | 0.68 | KDM4E (0.34) | HTTSMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL5264237 | 0.68 | CYP1A2 (0.41) | HTTSMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL7128812 | 0.68 | MAPT (0.40) | HTTSMN1; SMN2GAAMAPTMEN1 | |
| SCHEMBL23861392 | 0.67 | CDK4 (0.39) | APPHSP90AA1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170926-A1 | Antiviral agents | MONASH UNIVERISTY (AU) | 2009-07-02 | — | — | US | disclosed |
| US-20090170926-A1 | Antiviral agents | MONASH UNIVERISTY (AU) | 2009-07-02 | — | — | US | disclosed |
| US-20090170926-A1 | Antiviral agents | MONASH UNIVERISTY (AU) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170926-A1 | Antiviral agents | SLC10A1, HAVCR2, ZC3HAV1 | PTPN1 1233/4885HTT 4719/4885SMN1; SMN2 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.