Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ODC1 | P11926 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254656 | 0.89 | PTPN1 (0.56) | PTPN1XDHALOX5MGAMNPC1 | |
| SCHEMBL8723354 | 0.75 | XDH (0.68) | PTPN1XDHALOX5NPC1RAB9A | |
| SCHEMBL30140565 | 0.75 | XDH (0.68) | PTPN1XDHALOX5NPC1RAB9A | |
| Kanzonol W SCHEMBL29378682 | 0.74 | TYR (0.65) | PTPN1XDHALOX5TYRBCHE | |
| SCHEMBL8685142 | 0.73 | MAPT (0.71) | PTPN1XDHMGAMNPC1HSP90AA1 | |
| SCHEMBL27810630 | 0.71 | PTPN1 (0.52) | PTPN1XDHALOX5MGAMNPC1 | |
| SCHEMBL31254058 | 0.71 | PTPN1 (0.52) | PTPN1XDHALOX5MGAMNPC1 | |
| SCHEMBL4251941 | 0.71 | PTPN1 (0.40) | PTPN1XDHMGAMNPC1HSP90AA1 | |
| SCHEMBL13779564 | 0.71 | PTPN1 (0.40) | PTPN1XDHMGAMNPC1HSP90AA1 | |
| SCHEMBL24620599 | 0.69 | PTPN1 (0.34) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170926-A1 | Antiviral agents | MONASH UNIVERISTY (AU) | 2009-07-02 | — | — | US | disclosed |
| US-20090170926-A1 | Antiviral agents | MONASH UNIVERISTY (AU) | 2009-07-02 | — | — | US | disclosed |
| US-20090170926-A1 | Antiviral agents | MONASH UNIVERISTY (AU) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170926-A1 | Antiviral agents | SLC10A1, HAVCR2, ZC3HAV1 | PTPN1 1233/4885XDH 324/4885ALOX5 1919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.