Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253743 | 0.83 | APP (0.37) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL10026216 | 0.81 | KDM4E (0.32) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL7263829 | 0.81 | SIRT2 (0.38) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL30284250 | 0.81 | SIRT2 (0.38) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL30284405 | 0.80 | KDM4E (0.50) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL361847 | 0.80 | KDM4E (0.50) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL361958 | 0.79 | ALDH1A1 (0.32) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL7971753 | 0.78 | HTT (0.36) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL5264237 | 0.78 | CYP1A2 (0.41) | KDM4EMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL20848052 | 0.77 | KDM4E (0.39) | KDM4EMEN1NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| EP-1753838-B1 | POLYMERISABLE NAPHTHOPYRAN DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM SAID DERIVATIVES | POLYMEREXPERT S A (FR) | 2012-03-14 | — | — | EP | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| EP-1834195-B9 | PHOTOCHROMIC INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2010-07-21 | — | — | EP | disclosed |
| EP-1834195-B1 | PHOTOCHROMIC INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2010-03-17 | — | — | EP | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | CCND3, H1-3, H1-0 | KDM4E 2000/4885MEN1 2826/4885NPC1 898/4885 |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | C1S, H1-0, H1-3 | KDM4E 3155/4885MEN1 1443/4885NPC1 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.