Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.42 |
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958902 | 0.87 | CYP11B1 (0.41) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3964145 | 0.81 | PPARD (0.47) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3965826 | 0.78 | PPARD (0.43) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3970524 | 0.78 | PPARD (0.43) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3965823 | 0.78 | PPARD (0.43) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3965719 | 0.72 | PPARD (0.55) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3971905 | 0.69 | CYP11B1 (0.40) | FFAR1 | |
| SCHEMBL3964888 | 0.69 | CYP11B1 (0.41) | PPARDPPARAPPARG | |
| SCHEMBL3961775 | 0.69 | FFAR4 (0.41) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL3966163 | 0.69 | GSTP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | LTB4R2, LTC4S, LTB4R | PPARD 88/4885FFAR1 111/4885PPARA 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.