⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42379 | 0.92 | — | — | |
| SCHEMBL420528 | 0.91 | ALDH1A1 (0.52) | — | |
| SCHEMBL8500333 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL76042 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL104549 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL55807 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL1170322 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL2046899 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL4620117 | 0.90 | NAAA (0.61) | — | |
| SCHEMBL8496408 | 0.90 | NAAA (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3590 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986215-A | 2-Phenyl-4-acyl benzofurans, preparation and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | claimed |
| US-20230399320-A1 | NOVEL CAPSID ASSEMBLY INHIBITOR | Pelemed Co., Ltd. (UA) | 2023-12-14 | — | — | US | claimed |
| EP-4242203-A1 | NOVEL CAPSID ASSEMBLY INHIBITOR | Pelemed Co., Ltd. (KR) | 2023-09-13 | — | — | EP | claimed |
| US-20230201144-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | NOVOMEDIX, LLC (US) | 2023-06-29 | — | — | US | claimed |
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | claimed |
| EP-4157249-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | Novomedix, LLC (US) | 2023-04-05 | — | — | EP | claimed |
| WO-2021243319-A1 | BIARYLSULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE FOR TREATING FIBROTIC LUNG DISEASE | NOVOMEDIX, LLC (US) | 2021-12-02 | — | — | WO | claimed |
| US-20210347780-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC | 2021-11-11 | — | — | US | claimed |
| EP-3706899-A1 | BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS | The Government Of The United States Of America As The Secretary of The Navy (US) | 2020-09-16 | — | — | EP | claimed |
| US-20190134601-A1 | BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2019-05-09 | — | — | US | claimed |
| EP-0582810-A1 | Novel 7-(substituted)-8-(substituted)-9-(substituted amino)-6-demethyl-6-deoxyetracyclines as antibiotic agents | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0346847-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-20 | — | — | EP | claimed |
| EP-0331609-A2 | Angiotensin converting enzyme inhibitors having psychotropic effects | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-06 | — | — | EP | claimed |
| US-4863945-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0302826-A2 | Process for the preparation of unsaturated amino acid compounds | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | claimed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | claimed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| EP-0125684-B1 | 2-ALKYLTHIO-1-AMINOALKYL-2-PYRROLINE-3-CARBONITRILES, PROCESS FOR THEIR PREPARATION AND MEDICINES WITH ANTI-THROMBOTIC EFFECTS CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1987-07-08 | — | — | EP | claimed |
| EP-0214570-A2 | N-alkylated tripeptides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |