SCHEMBL425244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL426279	0.90	KDM4E (1.00)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL14955316	0.90	KDM4E (0.85)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL429219	0.82	KDM4E (0.74)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL17175747	0.82	MEN1 (0.86)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL5013137	0.82	KDM4E (0.85)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL5014738	0.81	KDM4E (0.83)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL5015899	0.80	KDM4E (0.82)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL4045544	0.80	KDM4E (0.82)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL429590	0.80	MEN1 (1.00)	ALDH1A1HPGDHSD17B10ALOX15KDM4E
	SCHEMBL16451251	0.80	MEN1 (0.75)	ALDH1A1HPGDHSD17B10ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.