Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3558294 | 0.98 | CPB2 (0.38) | CPB2FFAR3SLC1A2ALDH1A1F2 | |
| Trifluoroacetic Acid SCHEMBL4250032 | 0.93 | FFAR3 (0.38) | CPB2FFAR3SLC1A2ALDH1A1TDP1 | |
| Bicarbonate SCHEMBL9097152 | 0.80 | FFAR3 (0.39) | FFAR3ALDH1A1TDP1 | |
| Trifluoroacetic Acid SCHEMBL22191335 | 0.79 | ALDH1A1 (0.39) | SLC1A2ALDH1A1TDP1F2F11 | |
| Trifluoroacetic Acid SCHEMBL3663048 | 0.79 | CPB2 (0.36) | CPB2SLC1A2ALDH1A1DGAT1 | |
| Carbamic Acid SCHEMBL2480642 | 0.78 | ALDH1A1 (0.41) | FFAR3ALDH1A1TDP1 | |
| Acetic Acid SCHEMBL2860441 | 0.78 | ALDH1A1 (0.41) | FFAR3SLC1A2ALDH1A1 | |
| Cycloleucine SCHEMBL27551133 | 0.77 | NSD2 (0.39) | CPB2ALDH1A1TDP1 | |
| Trifluoroacetic Acid SCHEMBL28157949 | 0.77 | CPB2 (0.36) | CPB2FFAR3DGAT1 | |
| Carbamic Acid SCHEMBL28841417 | 0.76 | ALDH1A1 (0.39) | FFAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188084-B2 | Pyridinone and pyridazinone derivatives as inhibitors of poly (ADP-ribose) polymerase (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA. (IT) | 2012-05-29 | — | — | US | disclosed |
| US-20090176765-A1 | Pyridinone and Pyridazinone Derivatives as Inhibitors of Poly (Adp-Ribose) Polymerase (Parp) | MSD ITALIA S.R.L. (IT) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176765-A1 | Pyridinone and Pyridazinone Derivatives as Inhibitors of Poly (Adp-Ribose) Polymerase (Parp) | PARP1, PARP2, PARP3 | CPB2 1729/4885FFAR3 2866/4885SLC1A2 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.