SCHEMBL4253154

SCHEMBL4253154

Brc1c(Br)c(Br)c(C2CO2)c(Br)c1Br

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13610870 0.62 TSHR (0.32) TSHR
SCHEMBL2882122 0.58 KDM4E (0.31)
SCHEMBL83447 0.57 TSHR (0.56) TSHR
Perbromobenzene SCHEMBL27124 0.56 ALDH1A1 (0.50) TSHR
SCHEMBL11881165 0.53 TSHR (0.44) TSHR
SCHEMBL192021 0.53 TSHR (0.44) TSHR
SCHEMBL1756184 0.52
SCHEMBL5368873 0.52
Water SCHEMBL1127581 0.50 TSHR (0.41) TSHR
SCHEMBL10656649 0.50 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090053616-A1 HOLOGRAPHIC RECORDING MEDIUM KABUSHIKI KAISHA TOSHIBA 2009-02-26 US disclosed